RING-EXPANSION OF 7-CHLORO-2-OXABICYCLO[4.2.0]OCT-4-EN-3-ONES TO 2H-OXOCIN-2-ONES WITH BASE. FORMATION OF A NEW OXACYCLOOCTATRIENONE SYSTEM
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چکیده
منابع مشابه
4-Sulfenyl-2-carbamoyl-4-isoxazolin-3-ones: biological isostere to 4-chloro-2-carbamoyl-4-isoxazolin-3-ones.
4-Sulfenyl-2-carbamoyl-4-isoxazolin-3-ones (4) were designed on the basis of biological isosterism and prepared in four steps. Some of these compounds showed sufficient pre-emergent herbicidal activities against various kinds of weeds. Among the synthesized compounds, 2-(N-(4-chlorophenyl)-N-isopropylcarbamoyl)-4-ethylthio-5-methyl-4 -isoxazolin-3-one (4cd) exhibited the most promising activity.
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Synthesis of 4-[(2/4-chloro-/2,3-dichloro-/2/4-bromo-/2,4-dinitro-/4-nitrophenyl) anilinemethyl]6-t-butyl-2H-1-benzopyran-2-ones have been carried out. Synthesized compounds were characterized by 1HNMR, IR and other physical and analytical data. All of the synthesized compounds were evaluated for their antifungal activity against Aspergillus awamori and Sclerotium rolfsii and antibacterial acti...
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Barium salts of dibenzylidene cystines 8a-c were obtained from the reaction of Lcystine with benzaldehyde or its derivatives in the presence of barium hydroxide. Their reduction with zinc and hydrochloric acid in methanol yielded the Narylmethylcysteines ?9a-c?. These can, in turn, be converted by esterification into the methyl esters ?10 a-c. ?Reaction of N, N'-carbonyl diimidazole (Im C...
متن کاملAnticonvulsant Activities of 4-benzylidene-6-(4-methyl-phenyl)-4,5- dihydropyridazin-(2H)-ones and 4-benzylidene-6-(4-chloro- phenyl)-4,5-dihydropyridazin-(2H)-ones
RESEARCH ARTICLE Anticonvulsant Activities of 4-benzylidene-6-(4-methyl-phenyl)-4,5dihydropyridazin-(2H)-ones and 4-benzylidene-6-(4-chlorophenyl)-4,5-dihydropyridazin-(2H)-ones Mohammad Asif and Anita Singh Department of Pharmacy, GRD (P.G) Institute of Management and Technology, Dehradun, 2480009, India Department of Pharmaceutical Sciences, Kumaun University Campus, Bhimtal, Nainital, India
متن کاملA novel NHC-catalyzed transformation of 2H-chromene-3-carboxaldehydes to 3-methyl-2H-chromen-2-ones.
An unexpected transformation of 2H-chromene-3-carboxaldehydes to coumarin derivatives, mediated by NHC, is reported.
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ژورنال
عنوان ژورنال: Chemistry Letters
سال: 1984
ISSN: 0366-7022,1348-0715
DOI: 10.1246/cl.1984.1503